Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F9NL
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| Former ID |
DIB018471
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| Drug Name |
12S-HPETE
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| Synonyms |
12-(S)-hydroperoxyeicosatetraenoic acid; 12-(S)-HPETE
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H32O4
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| Canonical SMILES |
CCCCCC=CCC(C=CC=CCC=CCCCC(=O)O)OO
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| InChI |
1S/C20H32O4/c1-2-3-4-5-10-13-16-19(24-23)17-14-11-8-6-7-9-12-15-18-20(21)22/h7-11,13-14,17,19,23H,2-6,12,15-16,18H2,1H3,(H,21,22)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1
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| InChIKey |
ZIOZYRSDNLNNNJ-LQWMCKPYSA-N
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| CAS Number |
CAS 71774-10-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8249, 4266119, 8143293, 8616431, 14826969, 15249371, 26754759, 26754760, 39289881, 47364911, 47959452, 50076837, 50110771, 53800990, 57357916, 77144802, 92309737, 99300651, 99302169, 104046398, 113854188, 126525051, 137071982, 142970223, 164757246, 179205523, 227170720, 241130737, 242252371, 252371186, 252455461, 252463853
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| ChEBI ID |
CHEBI:15626
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Activator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2481). | |||
| REF 2 | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6155-60. | |||
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