Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F8RA
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| Former ID |
DAP000002
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| Drug Name |
Theophylline
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| Synonyms |
Bronchoretard; Cetraphylline; Chronophyllin; Dimethylxanthine; Elixophylline; Liquophylline; Pseudotheophylline; Afonilum Retard; Bronchodid Duracap; Elixophyllin SR; Somophyllin CRT; Spophyllin retard; Telbans DrySyrup; Teofilina [Polish]; Theal tablets; Theobid Duracap; Theodur Dry Syrup; Uniphyllin continus; Elixophyllin (TN); Elixophyllin(e); Pulmo-Timelets; Somophyllin-CRT; Somophyllin-DF; Theo-Organidin; Theoclear-200; Theodur G (TN); Theolair (TN); Theophylline (JP15); Theophylline-SR; Quibron-t (TN); Theo-Dur-Sprinkle; Theophylline-[8-3H; Theoclear L.A.-130; 1,3 Dimethylxanthine; 1,3-Dimethylxanthine; 1H-purine-2,6-dione
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| Drug Type |
Small molecular drug
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| Indication | Chronic obstructive pulmonary disease [ICD-11: CA22; ICD-10: J44, J44.9] | Approved | [1], [2] | |
| Therapeutic Class |
Bronchodilator Agents
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| Company |
Purdue Pharma
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| Structure |
 |
Download2D MOL |
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| Formula |
C7H8N4O2
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| Canonical SMILES |
CN1C2=C(C(=O)N(C1=O)C)NC=N2
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| InChI |
1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
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| InChIKey |
ZFXYFBGIUFBOJW-UHFFFAOYSA-N
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| CAS Number |
CAS 58-55-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9340, 68760, 603445, 855679, 3140219, 4657313, 5643002, 7847437, 7890742, 7980771, 8026207, 8144385, 8149549, 8151463, 10518342, 10528330, 10528902, 11335378, 11360617, 11363932, 11366494, 11369056, 11371683, 11373924, 11377218, 11406129, 11461589, 11466848, 11466901, 11467968, 11468021, 11484559, 11486376, 11486602, 11488658, 11490488, 11492168, 11494852, 11537637, 14772732, 17389715, 21317898, 22390364, 22391535, 24277677, 24900236, 24900474, 24900581, 26611941, 26679415
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| ChEBI ID |
CHEBI:28177
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| ADReCS Drug ID | BADD_D02195 | |||
| SuperDrug ATC ID |
R03DA04
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| SuperDrug CAS ID |
cas=000058559
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine receptor (ADOR) | Target Info | Antagonist | [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 413). | |||
| REF 2 | Non-corticosteroid therapy for the long-term control of asthma. Expert Opin Pharmacother. 2007 Sep;8(13):2077-87. | |||
| REF 3 | Emerging adenosine receptor agonists. Expert Opin Emerg Drugs. 2007 Sep;12(3):479-92. | |||
| REF 4 | Role of adenosine in airway inflammation in an allergic mouse model of asthma. Int Immunopharmacol. 2006 Jan;6(1):36-45. | |||
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