Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F5WX
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| Former ID |
DIB011991
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| Drug Name |
GSK768974
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| Synonyms |
PTH analog, GlaxoSmithKline/Unigene; Parathyroid hormone analog (oral, Enteripep), Unigene/GlaxoSmithKline
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| Indication | Osteoporosis [ICD-11: FB83.0; ICD-10: M85.8] | Phase 2 | [1] | |
| Company |
Unigene Laboratories Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Parathyroid hormone receptor (PTH2R) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class B/2 (Secretin family receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class B Secretin-like | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015535) | |||
| REF 2 | Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice. Bone. 2000 Oct;27(4):471-8. | |||
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