Drug Information
Drug General Information | Top | |||
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Drug ID |
D0F4QJ
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Former ID |
DIB010095
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Drug Name |
CR-5790
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Synonyms |
EP4 receptor antagonist (osteoarthritis), Rottapharm Madaus
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Indication | Osteoarthritis [ICD-11: FA00-FA05; ICD-9: 715] | Investigative | [1] | |
Company |
Rottapharm Madaus
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Target and Pathway | Top | |||
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Target(s) | Prostaglandin E2 receptor EP4 (PTGER4) | Target Info | Antagonist | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Inflammatory mediator regulation of TRP channels | ||||
Renin secretion | ||||
Pathways in cancer | ||||
NetPath Pathway | FSH Signaling Pathway | |||
IL2 Signaling Pathway | ||||
IL4 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | ||||
Reactome | Prostanoid ligand receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Prostaglandin Synthesis and Regulation | |||
GPCRs, Class A Rhodopsin-like | ||||
Vitamin D Receptor Pathway | ||||
Small Ligand GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 343). |
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