Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F0PK
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| Drug Name |
Indomethacin analog 2
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| Synonyms |
PMID28895472-Compound-21
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| Drug Type |
Small molecular drug
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| Company |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIVANDERBILT UNIVERSITY THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANI
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H14ClNO4
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| Canonical SMILES |
COC1=CC2=C(C=C1)N(C=C2CC(=O)O)C(=O)C3=CC=C(C=C3)Cl
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| InChI |
1S/C18H14ClNO4/c1-24-14-6-7-16-15(9-14)12(8-17(21)22)10-20(16)18(23)11-2-4-13(19)5-3-11/h2-7,9-10H,8H2,1H3,(H,21,22)
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| InChIKey |
DHEMTWWLRLOBKI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:71026
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dihydrodiol dehydrogenase type I (AKR1C3) | Target Info | Inhibitor; Antagonist; Blocker | [1] |
| Target's Patent Info | Dihydrodiol dehydrogenase type I (AKR1C3) | Target's Patent Info | [1] | |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Allopregnanolone biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Arachidonic acid metabolism | ||||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Reactome | Retinoid metabolism and transport | |||
| WikiPathways | Metapathway biotransformation | |||
| Benzo(a)pyrene metabolism | ||||
| Arachidonic acid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Dec;27(12):1329-1340. | |||
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