Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0EX2M
|
|||
| Former ID |
DNC006816
|
|||
| Drug Name |
1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine
|
|||
| Synonyms |
CHEMBL214240; 1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine; SCHEMBL5448643
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H21ClN2
|
|||
| Canonical SMILES |
C1CN(CCN1)C(CC2=CC(=CC=C2)Cl)C3=CC=CC=C3
|
|||
| InChI |
1S/C18H21ClN2/c19-17-8-4-5-15(13-17)14-18(16-6-2-1-3-7-16)21-11-9-20-10-12-21/h1-8,13,18,20H,9-12,14H2
|
|||
| InChIKey |
LTKQGPSHVUGDKE-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Norepinephrine transporter (NET) | Target Info | Inhibitor | [1] |
| Serotonin transporter (SERT) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | ||||
| 5HT3 type receptor mediated signaling pathway | ||||
| 5HT4 type receptor mediated signaling pathway | ||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| SIDS Susceptibility Pathways | ||||
| Synaptic Vesicle Pathway | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.