Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0EB4X
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| Former ID |
DNC010228
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| Drug Name |
2-Butyl-1(3)H-anthra[1,2-d]imidazole-6,11-dione
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| Synonyms |
CHEMBL593752
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H16N2O2
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| Canonical SMILES |
CCCCC1=NC2=C(N1)C=CC3=C2C(=O)C4=CC=CC=C4C3=O
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| InChI |
1S/C19H16N2O2/c1-2-3-8-15-20-14-10-9-13-16(17(14)21-15)19(23)12-7-5-4-6-11(12)18(13)22/h4-7,9-10H,2-3,8H2,1H3,(H,20,21)
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| InChIKey |
DSPOAQONKLYCKM-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
| KEGG Pathway | HTLV-I infection | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| Regulation of Telomerase | ||||
| IL2 signaling events mediated by PI3K | ||||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
| WikiPathways | TGF beta Signaling Pathway | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Telomere Maintenance | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28. | |||
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