Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E9TP
|
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| Former ID |
DAP000866
|
|||
| Drug Name |
Sulodexide
|
|||
| Indication | Tinnitus [ICD-11: MC41; ICD-10: H93.1; ICD-9: 388.3] | Approved | [1] | |
| Therapeutic Class |
Antithrombotic Agents
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C12H17N5O4
|
|||
| Canonical SMILES |
CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)OC
|
|||
| InChI |
1S/C12H17N5O4/c1-13-10-7-11(15-4-14-10)17(5-16-7)12-9(20-2)8(19)6(3-18)21-12/h4-6,8-9,12,18-19H,3H2,1-2H3,(H,13,14,15)/t6-,8-,9-,12-/m1/s1
|
|||
| InChIKey |
GRYSXUXXBDSYRT-WOUKDFQISA-N
|
|||
| CAS Number |
CAS 57817-83-1
|
|||
| PubChem Compound ID | ||||
| SuperDrug ATC ID |
B01AB11
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Antithrombin-III (ATIII) | Target Info | Activator | [2], [3] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathway Interaction Database | Glypican 1 network | |||
| Reactome | Intrinsic Pathway of Fibrin Clot Formation | |||
| Common Pathway of Fibrin Clot Formation | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24. | |||
| REF 2 | Review of pharmacodynamics, pharmacokinetics, and therapeutic properties of sulodexide. Med Res Rev. 1998 Jan;18(1):1-20. | |||
| REF 3 | Management of tinnitus: oral treatment with melatonin and sulodexide. J Biol Regul Homeost Agents. 2009 Apr-Jun;23(2):103-10. | |||
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