Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0E8JO
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| Former ID |
DIB001591
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| Drug Name |
FO-152
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| Synonyms |
AC1OCEZ1; FO-152; [(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S)-2-amino-3-methylbutanoate hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 2 | [1] | |
| Company |
Daiichi Fine Chemicals Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C14H21ClFN3O7
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| Canonical SMILES |
CC(C)C(C(=O)OCC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O)N.Cl
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| InChI |
1S/C14H20FN3O7.ClH/c1-5(2)8(16)13(22)24-4-7-9(19)10(20)12(25-7)18-3-6(15)11(21)17-14(18)23;/h3,5,7-10,12,19-20H,4,16H2,1-2H3,(H,17,21,23);1H/t7-,8+,9-,10-,12-;/m1./s1
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| InChIKey |
HMYHLEZOXXVLBU-LNKDGEPZSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003064) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2642). | |||
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