Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E7TO
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| Former ID |
DNC013570
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| Drug Name |
1-(1-(4-bromophenyl)ethylidene)thiosemicarbazide
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| Synonyms |
CHEMBL258261; NSC521067; AC1NSLKG; 16546-06-8; ZINC4709233; 4'-Bromoacetophenonethiosemicarbazone; BDBM50376212; AKOS002388584; AKOS008939483; NSC-521067
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H10BrN3S
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| Canonical SMILES |
CC(=NNC(=S)N)C1=CC=C(C=C1)Br
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| InChI |
1S/C9H10BrN3S/c1-6(12-13-9(11)14)7-2-4-8(10)5-3-7/h2-5H,1H3,(H3,11,13,14)/b12-6-
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| InChIKey |
OKNJXRBJRXAECS-SDQBBNPISA-N
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| CAS Number |
CAS 16546-06-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102. | |||
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