Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E6KN
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| Former ID |
DNCL003589
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| Drug Name |
GSK2647544
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| Synonyms |
GSK-2647544
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| Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Phase 1 | [1] | |
| Company |
GlaxoSmithKline
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Platelet-activating factor acetylhydrolase (PLA2G7) | Target Info | Modulator | [2] |
| KEGG Pathway | Ether lipid metabolism | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Pathway Interaction Database | Lissencephaly gene (LIS1) in neuronal migration and development | |||
| WikiPathways | IL1 and megakaryotyces in obesity | |||
| Synthesis, Secretion, and Deacylation of Ghrelin | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01924858) A Positron Emission Tomography (PET) Study to Investigate the Brain Biodistribution of 18F GSK2647544 in Healthy Subjects to Determine Its Ability to Cross the Blood-brain-barrier.. U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1432). | |||
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