Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E6JX
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| Former ID |
DNC009314
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| Drug Name |
KNI-10088
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| Synonyms |
KNI-10088; CHEMBL499956; BDBM50273733
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C33H38N4O6S
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| Canonical SMILES |
CC1(C(N(CS1)C(=O)C(C(CC2=CC=CC=C2)NC(=O)COC3=CC=C(C=C3)N)O)C(=O)NC4C(CC5=CC=CC=C45)O)C
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| InChI |
1S/C33H38N4O6S/c1-33(2)30(31(41)36-28-24-11-7-6-10-21(24)17-26(28)38)37(19-44-33)32(42)29(40)25(16-20-8-4-3-5-9-20)35-27(39)18-43-23-14-12-22(34)13-15-23/h3-15,25-26,28-30,38,40H,16-19,34H2,1-2H3,(H,35,39)(H,36,41)/t25-,26+,28-,29-,30+/m0/s1
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| InChIKey |
YGKGGCBHYIMPFH-DOWNBTJOSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Plasmepsin 2 (Malaria PLA2) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin. Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. | |||
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