Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E5XA
|
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| Former ID |
DCL000210
|
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| Drug Name |
R763
|
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| Drug Type |
Small molecular drug
|
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| Indication | Haematological malignancy [ICD-11: 2B33.Y] | Phase 1 | [1] | |
| Therapeutic Class |
Anticancer Agents
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C24H30FN7O
|
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| Canonical SMILES |
CC1=C(C=CC(=C1)NC2=NC=C(C(=N2)NC3C4CC(C3C(=O)N)C=C4)F)N5CCN(CC5)C
|
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| InChI |
1S/C24H30FN7O/c1-14-11-17(5-6-19(14)32-9-7-31(2)8-10-32)28-24-27-13-18(25)23(30-24)29-21-16-4-3-15(12-16)20(21)22(26)33/h3-6,11,13,15-16,20-21H,7-10,12H2,1-2H3,(H2,26,33)(H2,27,28,29,30)/t15-,16+,20+,21-/m1/s1
|
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| InChIKey |
KSOVGRCOLZZTPF-QMKUDKLTSA-N
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| CAS Number |
CAS 871357-89-0
|
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Rigel. | |||
| REF 2 | Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen. J Cancer Res Clin Oncol. 2010 Jan;136(1):99-113. | |||
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