Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0E1JP
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| Drug Name |
Montelukast
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| Synonyms |
Singulair; Montelukast [INN:BAN]; UNII-MHM278SD3E; MK 0476; CHEMBL787; MHM278SD3E; CHEBI:50730; 142522-28-9; Aerokast; Brondilat (TN)
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Phase 2/3 | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C35H36ClNO3S
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| Canonical SMILES |
CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O
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| InChI |
1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1
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| InChIKey |
UCHDWCPVSPXUMX-TZIWLTJVSA-N
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| CAS Number |
CAS 158966-92-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:50730
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN cysteinyl leukotriene receptor (CysLTR) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The COvid-19 Symptom MOntelukast Trial (COSMO) | |||
| REF 2 | As a potential treatment of COVID-19: Montelukast. Med Hypotheses. 2020 May 11;142:109828. | |||
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