Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D5CY
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Former ID |
DIB008170
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Drug Name |
Pradefovir
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Synonyms |
Remofovir; Pradefovir mesylate; Remofovir mesylate; Hepavir-B; ICN 2001-3; MB-06866; MB-6866; Pradefovir (oral, hepatitis B), Ligand/Chiva
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Drug Type |
Small molecular drug
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Indication | Hepatitis virus infection [ICD-11: 1E50-1E51; ICD-9: 573.3] | Phase 2 | [1] | |
Company |
Metabasis Therapeutics Inc
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Structure |
Download2D MOL |
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Formula |
C17H19ClN5O4P
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Canonical SMILES |
C1COP(=O)(OC1C2=CC(=CC=C2)Cl)COCCN3C=NC4=C(N=CN=C43)N
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InChI |
1S/C17H19ClN5O4P/c18-13-3-1-2-12(8-13)14-4-6-26-28(24,27-14)11-25-7-5-23-10-22-15-16(19)20-9-21-17(15)23/h1-3,8-10,14H,4-7,11H2,(H2,19,20,21)/t14-,28+/m0/s1
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InChIKey |
GWNHAOBXDGOXRR-HJFSHJIFSA-N
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CAS Number |
CAS 625095-60-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Hepatitis B virus Reverse transcriptase (HBV RT) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00230503) Dose-Ranging Study of Pradefovir in Patients With Compensated Hepatitis B. U.S. National Institutes of Health. | |||
REF 2 | DOI: 10.1128/AAC.01566-05 |
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