Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D5CJ
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| Former ID |
DIB008340
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| Drug Name |
SDZ-LAP-977
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| Synonyms |
SDZ-281-977
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| Indication | Psoriasis vulgaris [ICD-11: EA90; ICD-9: 696] | Discontinued in Phase 2 | [1] | |
| Company |
Novartis AG
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| Structure |
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Download2D MOL |
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| Formula |
C18H20O5
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| Canonical SMILES |
COC1=CC(=C(C=C1)OC)CCC2=CC(=C(C=C2)O)C(=O)OC
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| InChI |
1S/C18H20O5/c1-21-14-7-9-17(22-2)13(11-14)6-4-12-5-8-16(19)15(10-12)18(20)23-3/h5,7-11,19H,4,6H2,1-3H3
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| InChIKey |
GZOFTOHENYHNMS-UHFFFAOYSA-N
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| CAS Number |
CAS 150779-71-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine-protein kinase (PTK) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004738) | |||
| REF 2 | Structure-activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications. Bioorg Med Chem. 2008 Aug 15;16(16):7552-60. | |||
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