Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D2YZ
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| Former ID |
DIB005032
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| Drug Name |
BMTP-11
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| Synonyms |
IL-11Ralpha targeted proapoptotic peptide (prostate cancer), MD Anderson Cancer Center; IL-11Ralpha targeted proapoptotic peptide (prostate cancer), Mercator
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| Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Phase 1 | [1] | |
| Company |
MD Anderson Cancer Center
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 11 receptor alpha (IL11RA) | Target Info | Modulator | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Panther Pathway | Interleukin signaling pathway | |||
| WikiPathways | Interleukin-11 Signaling Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00872157) BMTP-11 in Patients With Castrate-Resistant Prostate Cancer With Bone Mets. U.S. National Institutes of Health. | |||
| REF 2 | Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clin Cancer Res. 2015 Jul 1;21(13):3041-51. | |||
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