Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CV8R
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| Drug Name |
US8524917, 12
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| Synonyms |
SCHEMBL786644; CHEMBL3651715; UJUPJZYUKBFHHO-UHFFFAOYSA-N; BDBM101039; US8524917, 12; US8563594, 170; 1-Benzyl-N-(3,4-difluorobenzyl)-6-isopropoxy-2-isopropyl-1H-indole-3-carboxamide
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C29H30F2N2O2
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| Canonical SMILES |
CC(C)C1=C(C2=C(N1CC3=CC=CC=C3)C=C(C=C2)OC(C)C)C(=O)NCC4=CC(=C(C=C4)F)F
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| InChI |
1S/C29H30F2N2O2/c1-18(2)28-27(29(34)32-16-21-10-13-24(30)25(31)14-21)23-12-11-22(35-19(3)4)15-26(23)33(28)17-20-8-6-5-7-9-20/h5-15,18-19H,16-17H2,1-4H3,(H,32,34)
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| InChIKey |
UJUPJZYUKBFHHO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | S1P3 receptor inhibitors for treating pain. US8563594. | |||
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