Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CO9B
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| Former ID |
DIB001264
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| Drug Name |
Ad-p53
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| Synonyms |
P53 gene therapy, Transgene/Schering-Plough; Ad-p53, Transgene/Schering-Plough
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199] | Phase 2 | [1] | |
| Colorectal cancer [ICD-11: 2B91.Z] | Phase 1 | [2] | ||
| Company |
Transgene SA
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03544723) Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.. U.S. National Institutes of Health. | |||
| REF 2 | Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol. 2003 Jul 1;21(13):2508-18. | |||
| REF 3 | Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer. Cancer Gene Ther. 2003 Mar;10(3):224-38. | |||
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