Drug Information
Drug General Information | Top | |||
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Drug ID |
D0CL9S
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Former ID |
DAP000698
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Drug Name |
Telbivudine
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Synonyms |
Epavudine; LLT; LdT; Sebivo; Telbivudin; Tyzeka; Telbivudine [USAN]; LDT600; NB 02B; NV 02B; L-Deoxythymidine; L-Thymidine; L-dT; LDT-600; NV-02B; Tyzeka (TN); Beta-L-Thymidine; Telbivudine (USAN/INN); Tyzake/Sebivo (TN); Tyzeka, Sebivo, Telbivudine; 1-(2-Deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-beta-L-erythropentafuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 2'-Deoxy-L-thymidine
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Drug Type |
Small molecular drug
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Indication | Hepatitis B virus infection [ICD-11: 1E51.0; ICD-10: B18.1] | Approved | [1] | |
Therapeutic Class |
Antiviral Agents
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Company |
Idenix
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Structure |
Download2D MOL |
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Formula |
C10H14N2O5
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Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
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InChI |
1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
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InChIKey |
IQFYYKKMVGJFEH-CSMHCCOUSA-N
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CAS Number |
CAS 3424-98-4
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PubChem Compound ID | ||||
PubChem Substance ID |
649439, 866449, 10253548, 12015420, 15220960, 15220961, 46234569, 46508706, 47208326, 50070122, 50070883, 57348574, 79679357, 81044332, 92721242, 99299522, 104234230, 104253286, 113442015, 113585147, 124757407, 125164211, 126619322, 126645820, 126662079, 134224136, 134337987, 135115725, 135611174, 135692211, 135778824, 137005934, 141758313, 152343276, 160657121, 160964596, 172919923, 174007441, 175267960, 176484712, 179150345, 184598259, 210279169, 210281492, 223454562, 223668197, 226495211, 241047041, 241075091, 249582920
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ChEBI ID |
CHEBI:63624
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ADReCS Drug ID | BADD_D02145 | |||
SuperDrug ATC ID |
J05AF11
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Drug Resistance Mutation (DRM) | Top | |||
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DRM | DRM Info |
Target and Pathway | Top | |||
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Target(s) | Hepatitis B virus Polymerase (HBV P) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B. Enferm Infecc Microbiol Clin. 2008 May;26 Suppl 7:32-8. | |||
REF 2 | Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success. Best Pract Res Clin Gastroenterol. 2008;22(6):1081-92. |
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