Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CE8J
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| Former ID |
DIB008751
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| Drug Name |
Genaconazole
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| Synonyms |
SM-8668; SM-8668 analogs; SM-9164; Sch-39304; Sch-42426; Sch-42427
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| Drug Type |
Small molecular drug
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| Indication | Fungal infection [ICD-11: 1F29-1F2F; ICD-10: B35-B49; ICD-9: 110-118] | Phase 1 | [1] | |
| Company |
Sumitomo Pharmaceuticals Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H15F2N3O3S
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| Canonical SMILES |
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)S(=O)(=O)C
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| InChI |
1S/C13H15F2N3O3S/c1-9(22(2,20)21)13(19,6-18-8-16-7-17-18)11-4-3-10(14)5-12(11)15/h3-5,7-9,19H,6H2,1-2H3/t9-,13-/m1/s1
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| InChIKey |
HFGZFHCWKKQGIS-NOZJJQNGSA-N
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| CAS Number |
CAS 120924-80-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Candida Cytochrome P450 51 (Candi ERG11) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent. Antimicrob Agents Chemother. 1990 Jun;34(6):980-4. | |||
| REF 2 | New targets and delivery systems for antifungal therapy. Med Mycol. 2000;38 Suppl 1:335-47. | |||
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