Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0CD8G
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| Drug Name |
PMID25726713-Compound-19
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| Drug Type |
Small molecular drug
|
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| Company |
IMPACT THERAPEUTICS, INC. CAI, Suixiong TIAN, Ye Edward WANG, Xiaozhu XIE, Kai LI, Sicun YU, Zenghui GU, Chengyun LIU, Lijun
|
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| Structure |
 |
Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Smoothened homolog (SMO) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Smoothened homolog (SMO) | Target's Patent Info | [1] | |
| KEGG Pathway | Hedgehog signaling pathway | |||
| Pathways in cancer | ||||
| Proteoglycans in cancer | ||||
| Basal cell carcinoma | ||||
| Panther Pathway | Hedgehog signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family | |||
| Hedgehog signaling events mediated by Gli proteins | ||||
| Reactome | Class B/2 (Secretin family receptors) | |||
| Hedgehog 'off' state | ||||
| Activation of SMO | ||||
| WikiPathways | Hedgehog Signaling Pathway | |||
| Hair Follicle Development: Organogenesis (Part 2 of 3) | ||||
| Hair Follicle Development: Induction (Part 1 of 3) | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| GPCR ligand binding | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hedgehog inhibitors: a patent review (2013 - present).Expert Opin Ther Pat. 2015 May;25(5):549-65. | |||
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