Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8FX
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| Drug Name |
Pyrithione Zinc
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| Synonyms |
Head & Shoulders Conditioner
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| Drug Type |
Small molecular drug
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| Indication | Seborrhoeic dermatitis [ICD-11: EA81] | Approved | [1] | |
| Company |
Warner Chilcott Co Llc
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| Structure |
 |
Download2D MOL
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| Formula |
C10H8N2O2S2Zn
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| Canonical SMILES |
C1=CC(=S)N(C=C1)[O-].C1=CC(=S)N(C=C1)[O-].[Zn+2]
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| InChI |
1S/2C5H4NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4H;/q2*-1;+2
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| InChIKey |
PICXIOQBANWBIZ-UHFFFAOYSA-N
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| CAS Number |
CAS 13463-41-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:32076
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fungal Proton pump (FPPCM) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Mechanism of the antimicrobial action of pyrithione: effects on membrane transport, ATP levels, and protein synthesis. Antimicrob Agents Chemother. 1978 Jul;14(1):60-8. | |||
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