Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8AP
|
|||
| Drug Name |
Mitapivat
|
|||
| Synonyms |
AG-348
Click to Show/Hide
|
|||
| Indication | Hereditary haemolytic anemia [ICD-11: 3A10.3; ICD-10: D58.8] | Approved | [1] | |
| Pyruvate kinase deficiency [ICD-11: 5C53.00] | Phase 2 | [2] | ||
| Company |
Agios
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C24H26N4O3S
|
|||
| Canonical SMILES |
C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5
|
|||
| InChI |
1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2
|
|||
| InChIKey |
XAYGBKHKBBXDAK-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 1260075-17-9
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Pyruvate kinase PKLR (PKLR) | Target Info | Activator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 216196. | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.