Drug Information
Drug General Information | Top | |||
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Drug ID |
D0C7ON
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Drug Name |
PMID28870136-Compound-43
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Drug Type |
Small molecular drug
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Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
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Structure |
Download2D MOL |
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Formula |
C10H14N4O4
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Canonical SMILES |
CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
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InChI |
1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3
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InChIKey |
KSCFJBIXMNOVSH-UHFFFAOYSA-N
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CAS Number |
CAS 479-18-5
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:4728
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Target and Pathway | Top | |||
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Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Adenosine nucleotides degradation | ||||
KEGG Pathway | Purine metabolism | |||
Pyrimidine metabolism | ||||
Nicotinate and nicotinamide metabolism | ||||
Metabolic pathways | ||||
Panther Pathway | Purine metabolism | |||
Pyrimidine Metabolism | ||||
Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
Reactome | Purine catabolism | |||
WikiPathways | Differentiation Pathway | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Metabolism of nucleotides |
References | Top | |||
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REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. |
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