Drug Information
Drug General Information | Top | |||
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Drug ID |
D0C6US
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Former ID |
DNC006344
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Drug Name |
4-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine
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Synonyms |
4-(6-methoxy-3,4-dihydronaphthalen-2-yl)pyridine; Dihydronaphthalene 11; AC1O70HL; SCHEMBL4513739; CHEMBL425054; BDBM8897
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H15NO
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Canonical SMILES |
COC1=CC2=C(C=C1)C=C(CC2)C3=CC=NC=C3
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InChI |
1S/C16H15NO/c1-18-16-5-4-14-10-13(2-3-15(14)11-16)12-6-8-17-9-7-12/h4-11H,2-3H2,1H3
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InChIKey |
QCWIENOGGDTTEN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B... J Med Chem. 2006 Apr 6;49(7):2222-31. |
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