Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C5RZ
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| Former ID |
DIB021097
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| Drug Name |
tyramine
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| Synonyms |
Tyramine; 4-(2-Aminoethyl)phenol; 51-67-2; 4-Hydroxyphenethylamine; p-Tyramine; 2-(4-Hydroxyphenyl)ethylamine; Uteramine; Tyramin; Tyrosamine; Tocosine; 4-Hydroxyphenylethylamine; Systogene; Phenol, 4-(2-aminoethyl)-; p-Hydroxyphenethylamine; Tenosin-wirkstoff; p-Hydroxyphenylethylamine; p-(2-Aminoethyl)phenol; 2-(p-Hydroxyphenyl)ethylamine; Phenethylamine, p-hydroxy-; p-beta-Aminoethylphenol; Phenol, p-(2-aminoethyl)-; Benzeneethanamine, 4-hydroxy-; Tyramine base; beta-Hydroxyphenylethylamine; NSC 249188; p-tyramine; [3H]tyramine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C8H11NO
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| Canonical SMILES |
C1=CC(=CC=C1CCN)O
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| InChI |
1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
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| InChIKey |
DZGWFCGJZKJUFP-UHFFFAOYSA-N
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| CAS Number |
CAS 51-67-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3766, 136967, 608127, 839997, 858070, 3134838, 5502075, 8143353, 8150088, 8153454, 10524949, 11111872, 11336093, 11361332, 11364107, 11366669, 11369231, 11371765, 11375541, 11377393, 11462304, 11484432, 11488554, 11490509, 11493615, 11495027, 15321440, 24715053, 24889929, 24900582, 25622217, 26512235, 26613119, 26679249, 26747190, 26747191, 26752293, 26752294, 29204652, 29224648, 41530225, 47291202, 47365262, 47515377, 47810820, 47959828, 47959829, 48035206, 49649954, 49748652
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| ChEBI ID |
CHEBI:15760
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Trace amine-associated receptor-1 (TAAR1) | Target Info | Agonist | [3], [4] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | G alpha (s) signalling events | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2148). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2150). | |||
| REF 3 | Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. PLoS One. 2011;6(10):e27073. | |||
| REF 4 | Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):8966-71. | |||
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