Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C4YX
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| Drug Name |
Carboxamide derivative 11
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| Synonyms |
PMID25399719-Compound-9
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| Drug Type |
Small molecular drug
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| Company |
ABBVIE DEUTSCHLAND [DEABBVIE INC [US]
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H30N6O4
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| Canonical SMILES |
C1CC1NC(=O)C(=O)C(CC2=CC=CC=C2)NC(=O)C3=C(N=CC=C3)N4C=CC(=N4)CN5CCOCC5
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| InChI |
1S/C27H30N6O4/c34-24(27(36)29-20-8-9-20)23(17-19-5-2-1-3-6-19)30-26(35)22-7-4-11-28-25(22)33-12-10-21(31-33)18-32-13-15-37-16-14-32/h1-7,10-12,20,23H,8-9,13-18H2,(H,29,36)(H,30,35)
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| InChIKey |
POGBERZVWORYJW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calpain-2 (CAPN2) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Calpain-2 (CAPN2) | Target's Patent Info | [1] | |
| KEGG Pathway | Protein processing in endoplasmic reticulum | |||
| Apoptosis | ||||
| Alzheimer's disease | ||||
| Reactome | Degradation of the extracellular matrix | |||
| WikiPathways | Focal Adhesion | |||
| Integrated Pancreatic Cancer Pathway | ||||
| Alzheimers Disease | ||||
| Integrin-mediated Cell Adhesion | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31. | |||
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