Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C3ZN
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| Drug Name |
Imidazopyridine derivative 6
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| Synonyms |
PMID28627961-Compound-15
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| Drug Type |
Small molecular drug
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| Company |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH PFAU, Roland ARNDT, Kirsten DOODS, Henri HAUEL, Norbert KLINDER, Klaus KUELZER, Raimund
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| Structure |
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Download2D MOL |
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| Formula |
C23H17BrF5N5O2
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| Canonical SMILES |
CN1C2=C(C=C(C(=N2)OCC(F)F)C(=O)NC3=CC=C(C=C3)Br)N=C1NC4=CC=CC=C4C(F)(F)F
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| InChI |
1S/C23H17BrF5N5O2/c1-34-19-17(32-22(34)31-16-5-3-2-4-15(16)23(27,28)29)10-14(21(33-19)36-11-18(25)26)20(35)30-13-8-6-12(24)7-9-13/h2-10,18H,11H2,1H3,(H,30,35)(H,31,32)
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| InChIKey |
KPWHFPJALLFSPY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E synthase (PTGES) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Prostaglandin E synthase (PTGES) | Target's Patent Info | [1] | |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.Expert Opin Ther Pat. 2017 Sep;27(9):1047-1059. | |||
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