Drug Information
Drug General Information | Top | |||
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Drug ID |
D0C2XT
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Former ID |
DIB019461
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Drug Name |
PMID24000170C36
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Synonyms |
GTPL7521
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C23H17F3N4O4
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Canonical SMILES |
CC1=C(C(=NO1)C)C2=CC3=NC=C4C(=C3N=C2OC)C(C(=O)N4)C5=CC=CC=C5OC(F)(F)F
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InChI |
1S/C23H17F3N4O4/c1-10-17(11(2)34-30-10)13-8-14-20(29-22(13)32-3)19-15(9-27-14)28-21(31)18(19)12-6-4-5-7-16(12)33-23(24,25)26/h4-9,18H,1-3H3,(H,28,31)
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InChIKey |
WWSIFGSLYORAET-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Bromodomain-containing protein 2 (BRD2) | Target Info | Inhibitor | [1] |
Bromodomain-containing protein 3 (BRD3) | Target Info | Inhibitor | [1] | |
Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] | |
NetPath Pathway | IL2 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Regulation of retinoblastoma protein | |||
WikiPathways | Chemical Compounds to monitor Proteins |
References | Top | |||
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REF 1 | Naphthyridines as novel BET family bromodomain inhibitors. ChemMedChem. 2014 Mar;9(3):580-9. |
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