Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C1TJ
|
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| Former ID |
DIB005455
|
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| Drug Name |
HN-10200
|
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| Indication | Cardiac failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9] | Discontinued in Phase 2 | [1] | |
| Company |
Nycomed AS
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C12H11N3O2S2
|
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| Canonical SMILES |
COC1=C(SC=C1S(=O)C)C2=NC3=C(N2)C=CC=N3
|
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| InChI |
1S/C12H11N3O2S2/c1-17-9-8(19(2)16)6-18-10(9)12-14-7-4-3-5-13-11(7)15-12/h3-6H,1-2H3,(H,13,14,15)
|
|||
| InChIKey |
WUXLGRPRVSOZPL-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase (PDE) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001592) | |||
| REF 2 | HN-10200 causes endothelium-independent relaxations in isolated canine arteries. Cardiovasc Drugs Ther. 1992 Apr;6(2):159-65. | |||
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