Drug Information
Drug General Information | Top | |||
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Drug ID |
D0BK3Z
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Former ID |
DIB013791
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Drug Name |
ProstaRex
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Synonyms |
AIT (prostate cancer), AltaRex; Protate cancer therapy, ViRexx/United Therapeutics; AIT (prostate cancer), ViRexx/United Therapeutics; Anti-idiotype induction therapy (prostate cancer), Paladin; Anti-idiotype induction therapy (prostate cancer), United Therapeutics; Anti-idiotype induction therapy (prostate cancer), AltaRex/United Therapeutics
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Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Investigative | [1] | |
Company |
AltaRex Medical Corp
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Target and Pathway | Top | |||
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Target(s) | Prostate specific antigen (KLK3) | Target Info | Modulator | [1] |
KEGG Pathway | Pathways in cancer | |||
Prostate cancer | ||||
Pathway Interaction Database | Coregulation of Androgen receptor activity | |||
Regulation of Androgen receptor activity | ||||
FOXA1 transcription factor network | ||||
Reactome | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | |||
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | ||||
WikiPathways | Prostate Cancer | |||
Androgen receptor signaling pathway |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2373). |
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