Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0BH2T
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| Former ID |
DNC013340
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| Drug Name |
2,2',4,4'-tetrahydroxychalcone
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| Synonyms |
2,4,2',4'-Tetrahydroxychalcone; 2,2',4,4'-tetrahydroxychalcone; CHEMBL394855; SCHEMBL675094; 2,4,2'',4''-tetrahydroxychalcone; LMPK12120128; 2,2'',4,4''-tetrahydroxychalcone; BDBM50203985
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H12O5
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| Canonical SMILES |
C1=CC(=C(C=C1O)O)C=CC(=O)C2=C(C=C(C=C2)O)O
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| InChI |
1S/C15H12O5/c16-10-3-1-9(14(19)7-10)2-6-13(18)12-5-4-11(17)8-15(12)20/h1-8,16-17,19-20H/b6-2+
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| InChIKey |
ZWTDXYUDJYDHJR-QHHAFSJGSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors. Bioorg Med Chem. 2007 Mar 15;15(6):2396-402. | |||
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