Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B9ZE
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| Former ID |
DIB019496
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| Drug Name |
PMID10602705C40
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| Synonyms |
H(3)N(+)CH(CH(2)CH(2)SO(3)(-))CH(SH)CO-Ile-(3-COOH)Pro; GTPL8630
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C17H29N3O9S2
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| Canonical SMILES |
CCC(C)C(C(=O)N1CCC(C1C(=O)O)C(=O)O)NC(=O)C(C(CCS(=O)(=O)O)N)S
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| InChI |
1S/C17H29N3O9S2/c1-3-8(2)11(19-14(21)13(30)10(18)5-7-31(27,28)29)15(22)20-6-4-9(16(23)24)12(20)17(25)26/h8-13,30H,3-7,18H2,1-2H3,(H,19,21)(H,23,24)(H,25,26)(H,27,28,29)/t8-,9?,10-,11+,12+,13-/m1/s1
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| InChIKey |
HUWSZNZAROKDRZ-RRLWZMAJSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamyl aminopeptidase (ENPEP) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Renin-angiotensin system | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme. J Med Chem. 1999 Dec 16;42(25):5197-211. | |||
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