Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B9UU
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| Former ID |
DNC009424
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| Drug Name |
BW-202W92
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| Synonyms |
BW-202W92; SCHEMBL136398; CHEMBL448556; QEDNOUAODRFJQN-UHFFFAOYSA-N; BW202W92; 2.4-Diamino-5-(2,3,5-trichlorophenyl)-6-fluoromethylpyrimidine; 2,4-diamino-5-(2,3,5-trichlorophenyl)-6-fluoromethylpyrimidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H8Cl3FN4
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| Canonical SMILES |
C1=C(C=C(C(=C1C2=C(N=C(N=C2N)N)CF)Cl)Cl)Cl
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| InChI |
1S/C11H8Cl3FN4/c12-4-1-5(9(14)6(13)2-4)8-7(3-15)18-11(17)19-10(8)16/h1-2H,3H2,(H4,16,17,18,19)
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| InChIKey |
QEDNOUAODRFJQN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Inhibitor | [1] |
| Voltage-gated sodium channel alpha Nav1.3 (SCN3A) | Target Info | Inhibitor | [1] | |
| Voltage-gated sodium channel alpha Nav1.4 (SCN4A) | Target Info | Inhibitor | [1] | |
| Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. J Med Chem. 2009 May 14;52(9):2694-707. | |||
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