Drug Information
Drug General Information | Top | |||
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Drug ID |
D0B5FA
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Drug Name |
Benzimidazole and imadazopyridine carboximidamide compound 2
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Synonyms |
PMID29473428-Compound-24
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C13H10BrN5O
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Canonical SMILES |
C1=CC(=CC(=C1)Br)N=C(C2=C3C(=NC=C2)N=CN3)NO
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InChI |
1S/C13H10BrN5O/c14-8-2-1-3-9(6-8)18-12(19-20)10-4-5-15-13-11(10)16-7-17-13/h1-7,20H,(H,18,19)(H,15,16,17)
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InChIKey |
UPPKJOIPXZWQCK-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target Info | Inhibitor | [1] |
Target's Patent Info | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target's Patent Info | [1] | |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation | ||||
L-kynurenine degradation | ||||
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
NAD de novo biosynthesis | ||||
KEGG Pathway | Tryptophan metabolism | |||
Metabolic pathways | ||||
African trypanosomiasis | ||||
NetPath Pathway | TSLP Signaling Pathway | |||
IL5 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | ||||
Pathwhiz Pathway | Tryptophan Metabolism | |||
Reactome | Tryptophan catabolism | |||
WikiPathways | Tryptophan metabolism | |||
Metabolism of amino acids and derivatives |
References | Top | |||
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REF 1 | A patent review of IDO1 inhibitors for cancer.Expert Opin Ther Pat. 2018 Apr;28(4):317-330. |
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