Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B5DX
|
|||
| Drug Name |
Aminopyrimidine derivative 3
|
|||
| Synonyms |
PMID25656651-Compound-12c
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
VERTEX PHARMACEUTICALS INCORPORATED
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C26H31F3N8OS
|
|||
| Canonical SMILES |
CC1=CC(=NN1)NC2=CC(=NC(=N2)SC3=CC=C(C=C3)NC(=O)CC(F)(F)F)N4CCC(CC4)N5CCCC5
|
|||
| InChI |
1S/C26H31F3N8OS/c1-17-14-22(35-34-17)31-21-15-23(37-12-8-19(9-13-37)36-10-2-3-11-36)33-25(32-21)39-20-6-4-18(5-7-20)30-24(38)16-26(27,28)29/h4-7,14-15,19H,2-3,8-13,16H2,1H3,(H,30,38)(H2,31,32,33,34,35)
|
|||
| InChIKey |
SFNFDXQNCXVCLJ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl (Bcr-Abl) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fusion protein Bcr-Abl (Bcr-Abl) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.