Drug Information
Drug General Information | Top | |||
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Drug ID |
D0B4NU
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Former ID |
DNC006080
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Drug Name |
PGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Gonadotropin-releasing hormone receptor (GNRHR) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
GnRH signaling pathway | ||||
NetPath Pathway | IL1 Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||
Reactome | Hormone ligand-binding receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
Peptide GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor. J Med Chem. 2006 Jan 26;49(2):637-47. |
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