Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A6NQ
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| Former ID |
DIB018788
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| Drug Name |
AHPN
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| Synonyms |
Ro 47-2077; 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid; CD437; CD 437
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C27H26O3
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| Canonical SMILES |
C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O
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| InChI |
1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
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| InChIKey |
LDGIHZJOIQSHPB-UHFFFAOYSA-N
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| CAS Number |
CAS 125316-60-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10243912, 14781189, 15328007, 15676134, 24724445, 26753174, 29312917, 49995528, 53788172, 57345179, 80475298, 85788664, 103344674, 103978817, 104384416, 124891579, 128472472, 135091121, 136368004, 136946597, 137163478, 140059764, 144115801, 162023153, 162248383, 162260503, 162312832, 163305694, 164839342, 172849980, 174006355, 178100433, 179149743, 204377885, 223704951, 226535571, 241182520, 241375492, 242059771, 249615587, 252215114, 252343221
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| ChEBI ID |
CHEBI:88334
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Retinoic acid receptor gamma (RARG) | Target Info | Agonist | [2] |
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Nuclear Receptors in Lipid Metabolism and Toxicity | ||||
| Mesodermal Commitment Pathway | ||||
| Endoderm Differentiation | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3431). | |||
| REF 2 | Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. J Med Chem. 1995 Dec 22;38(26):4993-5006. | |||
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