Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A4NO
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| Former ID |
DNC014008
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| Drug Name |
L-162313
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| Synonyms |
L-162,313; 151488-11-8; L-162313; CHEMBL288174; butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate; 5,7-Dimethyl-2-ethyl-3-[[4-[2-(n-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]imidazo-[4,5-b]-pyridine; 5,7-Dimethyl-2-ethyl-3-[[4-[2(N-butyloxycarbonylsulfonamido)-5-isobutyl-3-thienyl]phenyl]methyl]Imidazo[4,5,6]pyridine; L 162313; Lopac-L-1415; AC1O7G4F; Lopac0_000697; MLS002153426; SCHEMBL9132197; GTPL3936; C30H38N4O4S2; HMS3262K15
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C30H38N4O4S2
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| Canonical SMILES |
CCCCOC(=O)NS(=O)(=O)C1=C(C=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C(=NC4=C3N=C(C=C4C)C)CC
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| InChI |
1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)
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| InChIKey |
RINPELQWLUGERM-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
11111368, 11646401, 14911428, 17405258, 24278791, 43223692, 47720610, 50106511, 50106512, 53777803, 57264287, 80565157, 85231107, 90340748, 92304142, 103216664, 103979543, 114637026, 121361659, 124749924, 124880528, 129134295, 134351213, 135298187, 162247851, 163564651, 178100764, 234569739, 242177890, 252341892, 252559370
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3936). | |||
| REF 2 | Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem. 2008 Jul 15;16(14):6841-9. | |||
| REF 3 | Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorg Med Chem. 2010 Jun 15;18(12):4570-90. | |||
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