Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A3SQ
|
|||
| Former ID |
DNC002377
|
|||
| Drug Name |
3-benzofuran-2-yl-2-benzothiazol-2-yl-3-oxo-propanenitrile
|
|||
| Indication | Glioma [ICD-11: 2A00.0] | Investigative | [1] | |
| Melanoma [ICD-11: 2C30] | Investigative | [1] | ||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | AP endonuclease 1 (APEX1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Base excision repair | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| WikiPathways | Spinal Cord Injury | |||
| TSH signaling pathway | ||||
| Base Excision Repair | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines. Br J Cancer. 2011 Feb 15;104(4):653-63. | |||
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