Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A2NT
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| Drug Name |
PMID25522065-Compound-46
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| Drug Type |
Small molecular drug
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| Company |
TAKEDA PHARMACEUTICAL COMPANY LIMITED MASADA, Shinichi
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H37N3O4
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| Canonical SMILES |
CC1=C(C=CC2=C1C=C(N2C)CNCC3CCOCC3)NC(=O)C4=CC=C(C=C4)OCC5CCCO5
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| InChI |
1S/C29H37N3O4/c1-20-26-16-23(18-30-17-21-11-14-34-15-12-21)32(2)28(26)10-9-27(20)31-29(33)22-5-7-24(8-6-22)36-19-25-4-3-13-35-25/h5-10,16,21,25,30H,3-4,11-15,17-19H2,1-2H3,(H,31,33)/t25-/m0/s1
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| InChIKey |
ODYOYEADBNGJGQ-VWLOTQADSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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