Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09ZZW
|
|||
| Former ID |
DCL001255
|
|||
| Drug Name |
VX-759
|
|||
| Synonyms |
CHEMBL352911; 3-{isopropyl[(Trans-4-Methylcyclohexyl)carbonyl]amino}-5-Phenylthiophene-2-Carboxylic Acid; 3-[Isopropyl-(4-methyl-cyclohexanecarbonyl)-amino]-5-phenyl-thiophene-2-carboxylic acid; VX-759; 3-[isopropyl-(4-methylcyclohexanecarbonyl)amino]-5-phenyl-thiophene-2-carboxylic acid; VX759; NN3; VX 759; thiophene scaffold, 21; AC1L9XFB; NNI-2; 478025-29-5; SCHEMBL102322; CHEMBL561360; SCHEMBL1666872; SCHEMBL14376078; SCHEMBL13249635; BDBM35554; BDBM50139678; DB08279
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Phase 2 | [1] | |
| Company |
Vertex
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C22H27NO3S
|
|||
| Canonical SMILES |
CC1CCC(CC1)C(=O)N(C2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)C(C)C
|
|||
| InChI |
1S/C22H27NO3S/c1-14(2)23(21(24)17-11-9-15(3)10-12-17)18-13-19(27-20(18)22(25)26)16-7-5-4-6-8-16/h4-8,13-15,17H,9-12H2,1-3H3,(H,25,26)
|
|||
| InChIKey |
RZXQBIKGWSLVEK-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 478025-29-5
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 Pipeline of Vertex. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.