Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09YCW
|
|||
| Former ID |
DNC014694
|
|||
| Drug Name |
4-Amino-3-(5-methyl-thiophen-2-yl)-butyric acid
|
|||
| Synonyms |
133933-77-4; CHEMBL86144; 4-amino-3-(5-methylthiophen-2-yl)butanoic acid; 4-Amtba; 4-Amino-3-(5-methyl-2-thienyl)butyric acid; AC1L2PFE; ACMC-1C1U4; 4-Amino-3-(5-methyl-thiophen-2-yl)-butyric acid; SCHEMBL341475; CTK0H6620; beta-(5-Methyl-2-thienyl)GABA; BDBM50007107; AKOS022919013; 4-amino-3-(5-methylthien-2-yl)butanoic acid; 2-Thiophenepropanoic acid, beta-(aminomethyl)-5-methyl-, (+-)-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C9H13NO2S
|
|||
| Canonical SMILES |
CC1=CC=C(S1)C(CC(=O)O)CN
|
|||
| InChI |
1S/C9H13NO2S/c1-6-2-3-8(13-6)7(5-10)4-9(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)
|
|||
| InChIKey |
RPNWEWXYTFWDTR-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 133933-77-4
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| GABAergic synapse | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | Activation of G protein gated Potassium channels | |||
| G alpha (i) signalling events | ||||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Potassium Channels | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies. J Med Chem. 1991 Aug;34(8):2557-60. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.