Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09XWS
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| Former ID |
DNC007417
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| Drug Name |
1-(4-methoxyphenyl)-3-(1,3,4-thiadiazol-2-yl)urea
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| Synonyms |
CHEMBL389884; ZINC28225822
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H10N4O2S
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| Canonical SMILES |
COC1=CC=C(C=C1)NC(=O)NC2=NN=CS2
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| InChI |
1S/C10H10N4O2S/c1-16-8-4-2-7(3-5-8)12-9(15)13-10-14-11-6-17-10/h2-6H,1H3,(H2,12,13,14,15)
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| InChIKey |
WRRMEHJVEKNTQJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | LOX-5 messenger RNA (ALOX5 mRNA) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6. | |||
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