Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09XVQ
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| Former ID |
DIB013339
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| Drug Name |
PT-14
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| Synonyms |
Erectide; PT-14 (transmucosal); PT-14 (transmucosal), Palatin/TheraTech
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| Indication | Erectile dysfunction [ICD-11: HA01.1; ICD-10: N48.4; ICD-9: 302.72, 607.84] | Discontinued in Phase 2 | [1] | |
| Company |
Competitive Technologies Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H20N2O2
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| Canonical SMILES |
C1CCNC(C1)CCOC(=O)C2=CC=CC=C2N
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| InChI |
1S/C14H20N2O2/c15-13-7-2-1-6-12(13)14(17)18-10-8-11-5-3-4-9-16-11/h1-2,6-7,11,16H,3-5,8-10,15H2
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| InChIKey |
BMIJYAZXNZEMLI-UHFFFAOYSA-N
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| CAS Number |
CAS 87-21-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:135011
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanocortin receptor 4 (MC4R) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pathway Interaction Database | Syndecan-3-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010143) | |||
| REF 2 | The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice. Neuropeptides. 2014 Feb;48(1):47-51. | |||
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