Drug Information
Drug General Information | Top | |||
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Drug ID |
D09XUJ
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Drug Name |
PMID28870136-Compound-59
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Drug Type |
Small molecular drug
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Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
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Structure |
Download2D MOL |
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Formula |
C21H18N4O3
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Canonical SMILES |
C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=NN(C(=O)C=C4)CCCC(=O)O
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InChI |
1S/C21H18N4O3/c26-18-12-11-16(22-25(18)14-6-10-19(27)28)20-17-9-4-5-13-24(17)23-21(20)15-7-2-1-3-8-15/h1-5,7-9,11-13H,6,10,14H2,(H,27,28)
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InChIKey |
FKJPZJACCBMNKZ-UHFFFAOYSA-N
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CAS Number |
CAS 131185-37-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Adenosine nucleotides degradation | ||||
KEGG Pathway | Purine metabolism | |||
Pyrimidine metabolism | ||||
Nicotinate and nicotinamide metabolism | ||||
Metabolic pathways | ||||
Panther Pathway | Purine metabolism | |||
Pyrimidine Metabolism | ||||
Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
Reactome | Purine catabolism | |||
WikiPathways | Differentiation Pathway | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Metabolism of nucleotides |
References | Top | |||
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REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. |
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