Drug Information
Drug General Information | Top | |||
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Drug ID |
D09VAB
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Former ID |
DIB014596
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Drug Name |
BPR1K-0224
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Synonyms |
Aurora kinase inhibitors (cancer); BPR1K-0025; BPR1K-0432; BPR1K-0648; BPR1K-0724; Aurora kinase inhibitors (cancer), National Health Research Institutes
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
Company |
National Health Research Institutes
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Aurora kinase C (AURKC) | Target Info | Inhibitor | [1] |
KEGG Pathway | Oocyte meiosis | |||
Reactome | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | |||
Separation of Sister Chromatids | ||||
Resolution of Sister Chromatid Cohesion | ||||
RHO GTPases Activate Formins | ||||
WikiPathways | EGF/EGFR Signaling Pathway | |||
JAK/STAT | ||||
Gastric Cancer Network 1 | ||||
Integrated Breast Cancer Pathway | ||||
APC/C-mediated degradation of cell cycle proteins |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1936). |
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