Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09TNA
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| Former ID |
DNC014611
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| Drug Name |
1-(3-Amino-benzyl)-1H-indole-5-carboxamidine
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| Synonyms |
CHEMBL319122; 1-(3-Amino-benzyl)-1H-indole-5-carboxamidine; ZINC26750418
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H16N4
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| Canonical SMILES |
C1=CC(=CC(=C1)N)CN2C=CC3=C2C=CC(=C3)C(=N)N
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| InChI |
1S/C16H16N4/c17-14-3-1-2-11(8-14)10-20-7-6-12-9-13(16(18)19)4-5-15(12)20/h1-9H,10,17H2,(H3,18,19)
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| InChIKey |
PHWLXNIGOXPBJT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin... J Med Chem. 1983 Feb;26(2):294-8. | |||
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