Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09QKI
|
|||
| Former ID |
DIB012821
|
|||
| Drug Name |
PPL-100
|
|||
| Synonyms |
HIV protease inhibitors, Ambrilia; HIV protease inhibitors, Pharmacor; HIV protease inhibitors, Procyon; HIV protease inhibitors, TaiMed; MK-8122; P-1946; PL-337; HIV protease inhibitors, Merck & Co
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Phase 1 | [1] | |
| Company |
Pharmacor Inc
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C33H44N4O6S
|
|||
| Canonical SMILES |
CC(C)CN(C(CCCCNC(=O)C(C(C1=CC=CC=C1)C2=CC=CC=C2)NC(=O)OC)CO)S(=O)(=O)C3=CC=C(C=C3)N
|
|||
| InChI |
1S/C33H44N4O6S/c1-24(2)22-37(44(41,42)29-19-17-27(34)18-20-29)28(23-38)16-10-11-21-35-32(39)31(36-33(40)43-3)30(25-12-6-4-7-13-25)26-14-8-5-9-15-26/h4-9,12-15,17-20,24,28,30-31,38H,10-11,16,21-23,34H2,1-3H3,(H,35,39)(H,36,40)/t28-,31-/m0/s1
|
|||
| InChIKey |
QAHLFXYLXBBCPS-IZEXYCQBSA-N
|
|||
| CAS Number |
CAS 612547-11-2
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Protease (HIV PR) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Antiviral activity and cross-resistance profile of P-1946, a novel human immunodeficiency virus type 1 protease inhibitor. Antiviral Res. 2006 Jun;70(2):17-20. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.